pipeline musculoskeletal repair running

Pipeline

We are building an exciting pipeline of multiple assets with blockbuster potential, all targeting age-related diseases.

Our lead asset, leramistat, is a first-in-class MCM which restores the body’s inherent capacity to repair and regenerate damaged tissue. With strong results showing its potential in studies to date, our clinical program is evaluating the potential of leramistat to repair the musculoskeletal system across several settings.

Our pipeline offers the opportunity to develop multiple assets with the ability to restore hallmarks of health, giving us the chance to rethink how we manage chronic diseases and age-related decline.

Drug/Disease
Discovery Pre-clinical Phase 1 Phase 2 Phase 3

Discovery Pre-clinical Phase 1 Phase 2 Phase 3

Leramistat is an investigational first-in-class MCM which restores the body’s inherent capacity to repair and restore damaged tissue. With strong results in repair and support of hallmarks of health in studies to date, our clinical program is evaluating the potential of leramistat to repair the musculoskeletal system across several settings.

Discovery Pre-clinical Phase 1 Phase 2 Phase 3

Leramistat’s unique mode of action enables the prevention of damage whilst mobilising capacity to repair to restore the cross-talk between muscle and bone, offering potential as a novel treatment for degenerative muscle and bone loss.

Discovery Pre-clinical Phase 1 Phase 2 Phase 3

Leramistat’s also supports adaptive repair in scarred lung tissue caused by idiopathic pulmonary fibrosis (IPF). Leramistat has been granted both FDA Fast Track and Orphan Drug Designation (ODD) to support its development for this serious condition. You can access our expanded access policy here.

In addition, leramistat shows benefits in preserving hallmarks of health supporting multiple additional indications.

Discovery Pre-clinical Phase 1 Phase 2 Phase 3

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Discovery Pre-clinical Phase 1 Phase 2 Phase 3

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