How to Make a Regenerative Medicine
Regenerative medicine has long carried the aura of the mythic, from Prometheus’s eternally renewing liver to Wolverine’s capacity for accelerated repair.
15th July 2026The next era of medicine will think in biology.
The platform for adaptive repair
What if medicine is asking the wrong question? For decades medicine has organised biology into diseases: thousands of labels, targets and fragmented solutions. But Nature didn’t organise life that way. It built adaptive, integrated systems that sense stress, restore function and enable repair. Medicine thinks in diseases… Biology thinks in adaptation.
We believe the next era of medicine will think in biology. Instead of asking “How do we manage another disease?” it will ask “How do we restore the biology that enables repair?” Istesso is activating that conserved biology with oral mitochondrial Complex I modulators (MCMs). These systemic medicines restore the capacity of tissues to sense stress, control aberrant inflammation and repair. One biology. Multiple tissues. Regenerative by design. Lead programme leramistat is in Phase 2; the platform expands from there.
"The natural healing force within each one of us is the greatest force in getting well."
Latest news
Sarcopenia Market and Landscape
Sarcopenia represents one of the largest remaining untapped pharmaceutical markets. Defined by the progressive loss of skeletal muscle mass, strength, and physical performance with aging or chronic disease, it affects tens of millions of adults worldwide and drives enormous healthcare costs through falls, frailty, loss of independence, and increased mortality. This document outlines the current market and landscape of Sarcopenia, including the opportunities, challenges and strategic implications.
26th June 2026
Istesso initiates Phase 2 clinical trial of leramistat in sarcopenia
London, UK, 16th June 2026. Istesso, the leader in oral...
16th June 2026