Approach

The need to keep people healthy as they grow old is more urgent than ever. We believe in a future where chronic diseases can be healed, not just managed, and where the possibility of a disease-free life becomes a reality. Where we go from stopping, or slowing disease progression to restoring the body’s own capacity to repair itself and return to health.

At Istesso, we have identified a switch that can restore capacity to repair across multiple tissues and disease types. Our Mitochondrial Complex I modulators (MCMs) have a novel mechanism of action compared with classical complex I targeting agents. This enables them to repair and regenerate tissue, control inflammaging, and protect hallmarks of health offering the possibility of living free from disease. The same approach extends broadly to chronic diseases of aging.

Our platform combines proprietary models with deep know-how and insight, supporting our exciting and disruptive platform.